Utrecht University (UU) is a leading Research University in the Netherlands. Main activities include advancing academic research across diverse fields, providing high-quality education to students, and contributing to societal challenges through innovation and collaboration with global partners.
Role
Utrecht University is the Project Coordinator of NEOLIVER and leads the tasks in WP1-Requirements and specifications and WP9-Coordination and management of the innovation.
DWI – Leibniz Institute for Interactive Materials (DWI) is a non-profit research institute based in Aachen (Germany). The work performed by the institute focuses on research and development of Biomedical Materials, Sustainable Materials, and Information Materials.
Role
As partner in NEOLIVER, the DWI – Leibniz Institute for Interactive Materials leads the WP3-Material development, covering the research and development of the bioprinting ink based on multicellular spheroids to act as building blocks for a bioprinted liver.
Instituto de investigación Sanitaria Aragón (IISA) is the Health Research Institute that centralizes all the biomedical and clinical research performed at “Lozano Blesa” and “Miguel Servet” University Hospitals, Primary Health Care, University of Zaragoza and Aragon´s Institute of Health Sciences.
Role
As the leader of WP7-Bioconstruct in vivo validation, IISA contributes to NEOLIVER by designing and implementing the optimal strategy for vascularizing the bioprinted construct and validating its function in vivo.
Katholieke Universiteit Leuven (KUL) is a research-intensive, internationally oriented university that carries out both fundamental and applied research. The current research in KU Leuven covers nine key areas: 1. Human health, 2. Medical technologies, 3. Biosciences & environment, 4. Matter, materials & energy, 5. Nature unlimited, 6. Manufacturing & ICT, 7. Arts, religion & culture, 8. Economy, law & society, 9. Human behaviour.
PHOSPRINT IDIOTIKI KEFALAIOUXIKI ETAIREIA (PHOS) is a laser bioprinter developer focusing on the highly precise and rapid delivery of cells and other bio-inks on the substrates of interest for tissue regeneration and biosensor applications.
Role
In NEOLIVER, PHOS leads WP4-Bioprinter development, by using their experience in order to develop a laser-induced forward transfer printer to create the vascularized liver construct.
Betthera (BETT) is a consulting company based in Hradec Králové (Czech Republic). Betthera provides detailed assessments of economic and social impact and enables qualified decision making for development and implementation of medical and emerging technologies. In Regulatory Affairs, Betthera implements an effective quality management system (QMS) meeting the regulatory requirements in the field of medical devices.
Role
In NEOLIVER project, BETT leads the tasks related with technology assessment of bioprinted liver constructs and the regulatory and technical documentation to upscale NEOLIVER project for first in-human trials.
AMIRES is a consulting company specializing in research, development, and innovation projects, based in Prague, Czech Republic. Over the past 15 years, AMIRES has participated as a partner in more than 60 projects under the Horizon 2020 and Horizon Europe programmes. This involvement has enabled AMIRES to establish a large network of European R&D teams and companies. AMIRES focuses on strategically oriented innovation for business and societal impact. Its key expertise includes project management, dissemination, communication, exploitation activities, and Intellectual Property services.
Role
As partner in NEOLIVER, AMIRES coordinates communication and dissemination activities leading WP8-Dissemination, communication, exploitation and sustainability; and supports the project and financial management process (all WPs).
CSEM is a Swiss non-profit technology innovation center at the forefront of life sciences innovation. It develops advanced biosystems that integrate engineering and biological sciences to revolutionize healthcare, with a focus on personalized medicine, diagnostics, and regenerative medicine. Using cutting-edge technologies like AI, biomonitoring, and lab automation, CSEM bridges the gap between applied science and industry, creating impactful solutions for society.
Role
In NEOLIVER, CSEM leads WP2-Spheroid production, quality control and encapsulation, covering the development of multicellular spheroids as building blocks for bioprinting the liver constructs. CSEM will focus on the industrialization of technologies for spheroid encapsulation and tissue maturation.
Kugelmeiers (KUG) is a spin-off of the University of Zurich located in Erlenbach, Zurich (Switzerland). Kugelmeiers develops and markets 3D cell culture technologies that can be applied in scientific, diagnostic and therapeutic applications.
Role
In NEOLIVER, KUG brings the expertise in plates development to obtain uniform, sized-controlled and large-scale spheroid aggregation.
CELLnTEC Advanced Cell Systems (CnT) is a pioneering developer and producer of precision media for primary and stem cell research, and a supplier to the cell therapy and regenerative medicine industry. CnT technologies enable scientists to successfully traverse the basic to translational research continuum and to accelerate clinical application.
Role
As partner in NEOLIVER, CnT provides an optimized medium formulation for multicellular spheroids and ensures readiness for good manufacturing practices to transfer from laboratory to factory environment for later clinical applications.
Erasmus University Medical Centre (EMC) is the largest scientific university medical centre in Europe, and it is based in Rotterdam (Netherlands). EMC’s field of activity is broad and extends from illness to health and from individual to social healthcare.
Role
EMC main activities in NEOLIVER cover the tasks related to clinical implementation and development of future strategies.